Ferrous gluconate is another iron supplement commonly used as a hematinic to address iron-deficiency anemia. Like ferrous sulfate, ferrous gluconate provides a source of bioavailable iron to support the synthesis of hemoglobin in red blood cells. Role of Ferrous Gluconate in Hematinics 1. Iron Supplementation: Ferrous gluconate serves as a source of elemental iron, a […]
Hematinics promote the formation of hemoglobin, the iron-containing pigment in red blood cells responsible for oxygen transport. These substances are vital for producing and maintaining healthy red blood cells and are crucial in preventing and treating various forms of anemia. Hematinics often addresses conditions characterized by a deficiency in hemoglobin or red blood cells, leading […]
Sodium potassium tartrate, commonly known as Rochelle salt, is a chemical compound with the molecular formula KNaC₄H₄O₆·4H₂O. It is a double salt of tartaric acid, composed of one molecule of potassium sodium tartrate and four molecules of water of crystallization. 1. Mechanism of Action Irritation of Gastrointestinal Tract: Sodium potassium tartrate irritates the stomach lining […]
Evaluating semi-solid dosage forms is critical in ensuring their quality, safety, and efficacy. Various tests and assessments are conducted to verify these pharmaceutical formulations’ physical, chemical, and microbiological attributes. Here is an overview of the key aspects considered during the evaluation of semi-solid dosage forms such as ointments, creams, gels, and pastes: 1. Physical Characteristics […]
Excipients are essential components in the formulation of semi-solid dosage forms, contributing to these pharmaceutical preparations’ stability, consistency, and performance. Semi-solid dosage forms, including ointments, creams, gels, and pastes, rely on various excipients to achieve desired physical and chemical properties. Here’s a detailed note on the common excipients used in semi-solid dosage forms: 1. Base […]
Crams and gels are prepared by creating semisolid dosage forms for topical application. These formulations are widely used in dermatological and cosmetic applications. Here are general guidelines for preparing creams and gels: Ingredients 1. Base Material: The base combines water and oil, often stabilized by an emulsifier. Common bases include oil-in-water (O/W) or water-in-oil (W/O) […]
Preparing ointments and pastes involves creating semisolid dosage forms designed for topical application. These formulations are commonly used in dermatological and topical drug delivery applications. Below are general guidelines for preparing ointments and pastes: Ingredients 1. Base Material: Choose a suitable base, often a combination of oils and fats. Common bases include white petrolatum, mineral […]
Dermal penetration refers to the process by which drugs or active substances traverse the layers of the skin to reach systemic circulation or exert their therapeutic effects locally. The skin is a barrier that protects the body, and dermal penetration involves overcoming this barrier for effective drug delivery. Classification Dermal penetration can be classified into […]
Pharmaceutical formulations that bridge the consistency between a liquid and a solid are known as semisolid dosage forms. These formulations are designed for topical application to the skin or mucous membranes. They encompass creams, ointments, gels, and pastes, distinguished by their semi-solid nature, enabling easy application, adherence to the skin or mucous membranes, and controlled […]
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