Definition: Tetracyclines are a group of broad-spectrum antibiotics that belong to the class of polyketides. They are derived from Streptomyces bacteria and are characterized by a four-ring structure. Tetracyclines exert their antibacterial effects by inhibiting protein synthesis in bacteria, binding to the 30S ribosomal subunit, thereby preventing the attachment of …
DeepakRajput 
“Applied Physiology in Health and Illness” by Ross and Wilson: Unveiling the Essence of Physiology
Greetings, aspiring healthcare champions! Are you ready to embark on a transformative journey through the fascinating realm of physiology? Look no further, because we’ve uncovered the perfect roadmap just for you – “Applied Physiology in Health and Illness” by the renowned Ross and Wilson! Imagine a world where complex scientific …
Drugs Used in Glaucoma
Glaucoma refers to a group of eye disorders characterized by damage to the optic nerve, often associated with increased intraocular pressure (IOP), which can lead to vision loss and blindness if left untreated. Management of glaucoma primarily involves the use of medications aimed at lowering IOP to prevent further damage …
Drugs Used in Myasthenia Gravis
Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by muscle weakness and fatigue, typically resulting from antibodies targeting the acetylcholine receptors (AChR) at the neuromuscular junction. Treatment of MG primarily involves the use of medications aimed at improving neuromuscular transmission and reducing symptoms. Here’s a detailed note covering the …
Local Anesthetic Agents
Local anesthetic agents are medications used to induce reversible loss of sensation in a specific area of the body, without causing loss of consciousness. They are widely employed in various medical procedures to alleviate pain and discomfort. Here’s a detailed note covering their definition, classification, pharmacological actions, doses, indications, and …
Neuromuscular blocking agents (NMBAs) and skeletal muscle relaxants (peripheral)
Neuromuscular blocking agents (NMBAs) and skeletal muscle relaxants (peripheral) are classes of drugs used to induce muscle relaxation in surgical and critical care settings. They act at the neuromuscular junction to inhibit or block the transmission of nerve impulses from motor neurons to skeletal muscle fibres, leading to paralysis or …
Sympatholytics, adrenergic blockers or adrenergic antagonists
Sympatholytics, adrenergic blockers, or adrenergic antagonists Sympatholytics, also known as adrenergic blockers or adrenergic antagonists, are a class of drugs that inhibit the actions of the sympathetic nervous system by blocking adrenergic receptors. These receptors are targets for the neurotransmitters adrenaline (epinephrine) and noradrenaline (norepinephrine), and their activation leads to …
