Adrenaline (epinephrine): Synthesis and Significance

Adrenaline, also known as epinephrine, is a vital hormone and neurotransmitter involved in the body’s fight-or-flight response. It plays a crucial role in regulating cardiovascular function, metabolism, and stress responses. This detailed note explores the synthesis, biological roles, and clinical significance of adrenaline. Synthesis of Adrenaline Adrenaline is synthesized from …

Noradrenaline (Norepinephrine): Synthesis and Significance

Noradrenaline, also known as norepinephrine, is a crucial neurotransmitter and hormone involved in the regulation of various physiological processes, including the fight-or-flight response, attention, arousal, and mood. It is synthesized primarily in the adrenal medulla and the locus coeruleus in the brain. This detailed note explores the synthesis, biological roles, …

Dopamine: Synthesis and Significance

Dopamine is a crucial neurotransmitter and hormone that plays vital roles in the central nervous system and peripheral tissues. It is involved in several key physiological processes including motor control, motivation, reward, and regulation of mood. Dopamine dysregulation is implicated in various neurological and psychiatric disorders. This note provides a …

Melatonin: Synthesis and Significance

Melatonin is a hormone primarily produced by the pineal gland in the brain and is a critical regulator of the sleep-wake cycle and various circadian rhythms. It has additional roles in antioxidant defense, immune function, and seasonal biological rhythms. This note provides a comprehensive overview of melatonin synthesis, its biological …

5-HT (Serotonin): Synthesis and Significance

5-HT, or serotonin, is a vital neurotransmitter with a broad range of physiological functions, influencing mood, appetite, sleep, and other behaviors. It also plays roles in the gastrointestinal system, cardiovascular system, and hemostasis. The significance of serotonin extends from its influence on mental health to its involvement in various bodily …

Catabolism of Phenylalanine and Tyrosine and Their Metabolic Disorders

Phenylalanine and tyrosine are essential amino acids involved in the synthesis of proteins and important biomolecules such as neurotransmitters, hormones, and pigments. Their catabolism is tightly regulated, and disruptions in these pathways can lead to serious metabolic disorders. This note provides a detailed overview of the catabolism of phenylalanine and …

The Urea Cycle and Its Disorders

The urea cycle, also known as the ornithine cycle, is a crucial metabolic pathway in the liver that converts toxic ammonia into urea for excretion from the body. Ammonia is a byproduct of amino acid and protein metabolism, and its accumulation can be toxic, particularly to the central nervous system. …

Amino Acid Metabolism: General Reactions of Amino Acid Metabolism

Amino acid metabolism encompasses a series of biochemical processes responsible for the synthesis, breakdown, and interconversion of amino acids. These reactions are crucial for maintaining the body’s protein balance and supporting various physiological functions. The primary reactions involved in amino acid metabolism include transamination, deamination, and decarboxylation.  1. Transamination Definition: …

Structural Isomerism in Organic Compounds

Structural isomerism, also known as constitutional isomerism, occurs when compounds have the same molecular formula but different arrangements of atoms in their structures. This type of isomerism is prevalent in organic chemistry and can significantly affect the physical and chemical properties of compounds. Structural isomerism can be classified into several …

Common and IUPAC Systems of Nomenclature of Organic Compounds

Nomenclature is the system of naming chemical compounds in a standardized way. Organic compounds can be named using two main systems: the common (or trivial) system and the International Union of Pure and Applied Chemistry (IUPAC) system. Common Nomenclature System The common system of nomenclature often uses historical or traditional …

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