Pellets are small, free-flowing, spherical or semi-spherical solid units typically ranging from 500 to 1500 micrometers in diameter. They are formed from powders or granules of active pharmaceutical ingredients (APIs) and excipients and are designed for oral administration. Pellets can be filled into capsules, compressed into tablets, or used for controlled release, immediate release, or … Read more
Packing storage of soft gelatin capsules: Soft gelatin capsules (softgels) are widely used dosage forms for delivering liquid, semi-solid, or paste-like contents. Due to their unique composition—primarily gelatin, plasticizers, and water—these capsules are sensitive to environmental factors such as humidity, temperature, and oxygen. Therefore, proper packaging, storage, and rigorous stability testing are critical to ensure … Read more
Soft Gelatin capsules: Quality control testing is essential in the manufacturing of soft gelatin capsules to ensure the product meets pharmacopeial specifications, maintains its integrity throughout its shelf life, and delivers the intended therapeutic effect. Quality control (QC) procedures are divided into two main phases: in-process testing and final product testing. Both phases are critical … Read more
Importance of Base Adsorption: Soft gelatin capsules are widely used in pharmaceutical formulations for encapsulating liquids, semi-solids, and suspensions that are not amenable to hard gelatin capsules. The success of any soft gelatin capsule product depends not only on the active pharmaceutical ingredient (API) but also on the careful selection and handling of the excipients, … Read more
Soft gelatin capsules, commonly referred to as soft gels, are a popular pharmaceutical dosage form that encapsulates a liquid or semi-solid substance within a soft, flexible gelatin-based shell. These capsules are widely utilized for the oral administration of a variety of pharmaceuticals and dietary supplements, including fat-soluble vitamins, essential oils, and drugs with poor water … Read more
DSSSB Pharmacist Syllabus 2025: Are you aspiring to secure a position as a Pharmacist under the Delhi Subordinate Services Selection Board (DSSSB)? Then, understanding the DSSSB Pharmacist Syllabus 2025 and Exam Pattern is absolutely crucial for crafting an effective preparation strategy. The DSSSB has meticulously designed the syllabus and exam format to evaluate candidates’ technical … Read more
In clinical research, precision and specificity are becoming increasingly important as medicine shifts from generalized treatment strategies to patient-centered care. Targeted clinical investigations represent a specialized approach where clinical trials are designed with narrowly defined objectives and populations. These investigations focus on specific hypotheses, therapeutic interventions, or patient subgroups, often with the intention of improving … Read more
Comparative Observational Studies: Observational studies hold a central and indispensable place in the realm of clinical research and epidemiology. Unlike experimental designs such as randomized controlled trials (RCTs), where researchers deliberately assign exposures to study their effects on outcomes, observational studies passively observe individuals in real-world settings without intervention. This approach reflects actual scenarios and … Read more
While passive surveillance relies on spontaneous or voluntary reporting, active surveillance involves proactive, organized, and systematic efforts to detect, collect, and assess information about adverse drug reactions (ADRs) or vaccine-related events. It is considered more reliable for assessing causality, estimating incidence rates, and evaluating drug safety in specific populations. Active Surveillance Active surveillance is critical … Read more
Passive Surveillance in Pharmacovigilance: Pharmacovigilance plays a pivotal role in ensuring the safety of medicinal products, including vaccines, throughout their life cycle. Among the various techniques employed in pharmacovigilance, passive surveillance remains one of the most extensively used due to its feasibility, broad scope, and utility in the early detection of safety signals. Understanding Passive … Read more
