B.pharma

Adrenergic Receptors: Alpha & Beta

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Adrenergic Receptors

Adrenergic receptors, also referred to as adrenoceptors, are integral membrane proteins that mediate the physiological effects of the catecholamine neurotransmitters adrenaline (epinephrine) and noradrenaline (norepinephrine). These receptors are primarily involved in the regulation and modulation of the sympathetic division of the autonomic nervous system. Based on their pharmacological profiles, receptor affinity, intracellular signaling mechanisms, and … Read more

Biosynthesis & Catabolism of Catecholamine

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Adrenergic Neurotransmitters

Biosynthesis & Catabolism of Catecholamine: Adrenergic neurotransmitters are essential for the transmission of signals in the sympathetic nervous system, influencing various physiological processes including heart rate, blood pressure, and stress responses. This note explores the biosynthesis and catabolism of catecholamines, focusing on adrenaline (epinephrine), noradrenaline (norepinephrine), and dopamine. Adrenergic Neurotransmitters: Biosynthesis and Catabolism of Catecholamine … Read more

Gonorrhea: Definition, and Treatment

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Gonorrhea

Gonorrhea Gonorrhea is a common sexually transmitted infection (STI) caused by the Gram-negative diplococcus Neisseria gonorrhoeae. It primarily infects mucous membranes of the urethra, cervix, rectum, pharynx, and conjunctiva, leading to various clinical manifestations depending on the site of infection. In females, it can remain asymptomatic, allowing the disease to progress silently, whereas in males, … Read more

Syphilis: Definition, and Treatment

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Syphilis

Syphilis Syphilis is a chronic systemic infectious disease caused by the spirochete bacterium Treponema pallidum subspecies pallidum. It is primarily transmitted through sexual contact, but can also be congenitally acquired. Known for its multistage progression, if left untreated, syphilis may lead to serious cardiovascular, neurological, and dermatological complications over time. Once on the decline due … Read more

AIDS: Definition, and Treatment

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AIDS

AIDS Acquired Immunodeficiency Syndrome (AIDS) represents the most advanced stage of infection caused by the Human Immunodeficiency Virus (HIV). It is a chronic, life-threatening condition characterized by a profound weakening of the immune system, which renders the body highly susceptible to opportunistic infections, malignancies, and neurological complications. Since its emergence in the early 1980s, AIDS … Read more

Urinary Tract Infections (UTIs): Treatment

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Urinary Tract Infection

Urinary Tract Infections Urinary Tract Infections (UTIs) are one of the most common bacterial infections encountered globally, affecting individuals across all age groups, with a pronounced prevalence among women. A UTI can involve any part of the urinary system, which includes the kidneys, ureters, bladder, and urethra. While generally curable with timely antibiotic therapy, untreated … Read more

Tuberculosis (TB): Definition Treatments

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Screenshot 2025 04 18 173840 Tuberculosis (TB): Definition Treatments

Tuberculosis Tuberculosis (TB) is a chronic infectious disease caused by the Mycobacterium tuberculosis complex, primarily affecting the lungs but capable of involving almost any organ system in the body. TB has been one of humanity’s deadliest diseases for centuries and continues to remain a leading cause of morbidity and mortality worldwide, especially in low- and … Read more

Leprosy (Hansen’s Disease)

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Leprosy

Leprosy Leprosy, also known as Hansen’s disease, is a chronic infectious disease that primarily affects the skin, peripheral nerves, mucosa of the upper respiratory tract, and eyes. Caused by the bacterium Mycobacterium leprae, it is one of the oldest recorded diseases in human history and carries a significant social stigma, largely due to disfigurement and … Read more

Typhoid Fever: Definition, Treatments

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Typhoid fever

Typhoid Fever Typhoid fever, also known simply as typhoid, is a systemic infectious disease caused by the bacterium Salmonella enterica serovar Typhi (S. Typhi). It is a life-threatening illness primarily affecting the gastrointestinal tract and can lead to severe complications if not diagnosed and treated in time. The disease remains a major public health challenge … Read more

Meningitis: Definition Type, and Treatment

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meningitis

Meningitis Meningitis represents a potentially life-threatening clinical syndrome characterized by inflammation of the protective membranes—known as the meninges—surrounding the brain and spinal cord. It is a condition of considerable global health concern, known to affect individuals of all age groups, with neonates, children, and immunocompromised individuals being the most susceptible. The disease may progress rapidly, … Read more