Introduction: Drug metabolism, a crucial aspect of pharmacokinetics, encompasses the enzymatic processes that transform drugs into metabolites within the body. Several factors influence drug metabolism, including genetic variability, environmental factors, drug-drug interactions, and stereochemical aspects. This note provides a comprehensive overview of the factors affecting drug metabolism, with a particular …
DeepakRajput 
Drug Metabolism: Principles, Phase I, and Phase II Reactions
Introduction: Drug metabolism refers to the enzymatic transformation of drugs and xenobiotics within the body, leading to the formation of metabolites that are often more hydrophilic and easier to excrete. This process plays a crucial role in drug efficacy, bioavailability, and toxicity. Understanding the principles and mechanisms of drug metabolism …
History and Development of Medicinal Chemistry
Introduction: The history and development of medicinal chemistry trace the evolution of mankind’s quest for therapeutic solutions to alleviate suffering and combat diseases. From ancient herbal remedies to modern molecular design, this note provides a comprehensive overview of the key milestones, influential figures, and pivotal discoveries that have shaped the …
Introduction to Medicinal Chemistry
Introduction: Medicinal chemistry is a multidisciplinary field that combines principles of chemistry, biology, and pharmacology to discover, design, develop, and optimize small molecule compounds for therapeutic use. It plays a pivotal role in the discovery and development of drugs to treat various diseases, ranging from infections to cancer. This note …
