Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels (hyperglycemia) resulting from defects in insulin secretion, insulin action, or both. It can lead to serious health complications if not properly managed. Types of Diabetes 1. Type 1 Diabetes: An autoimmune condition where the body’s immune system attacks insulin-producing beta cells in […]
Hemophilia is a rare genetic bleeding disorder characterized by the deficiency or dysfunction of clotting factors in the blood, primarily factor VIII (hemophilia A) or factor IX (hemophilia B). This results in prolonged or spontaneous bleeding episodes, which can lead to serious complications. This note explores the causes, types, symptoms, diagnosis, treatment, and management strategies […]
Anemia is a condition characterized by a deficiency in the number or quality of red blood cells (RBCs) or hemoglobin, leading to reduced oxygen-carrying capacity of the blood. Anemia can be broadly categorized into hereditary and acquired types, based on its underlying cause. This note explores the causes, pathophysiology, symptoms, diagnosis, treatment, and prevention of […]
A thalassemia is a group of inherited blood disorders characterized by the body’s inability to produce sufficient and functional hemoglobin, resulting in anemia. Hemoglobin, the protein in red blood cells responsible for carrying oxygen, has two main components: alpha and beta globin chains. Thalassemia is categorized based on which globin chain is affected: alpha thalassemia […]
Sickle cell anemia is a hereditary blood disorder characterized by the production of abnormal hemoglobin, known as hemoglobin S (HbS). This leads to the deformation of red blood cells into a sickle shape, which causes various complications including pain, anemia, infections, and organ damage. This note explores the genetic basis, pathophysiology, symptoms, diagnosis, treatment, and […]
Megaloblastic anemia is a type of anemia characterized by the presence of abnormally large, immature red blood cells (megaloblasts) in the bone marrow and peripheral blood. This condition primarily results from deficiencies in vitamin B12 (cobalamin) and/or folic acid (vitamin B9). These vitamins are crucial for DNA synthesis and red blood cell production. This note […]
Iron deficiency is one of the most common nutritional disorders worldwide, affecting individuals of all ages. It occurs when the body lacks enough iron to produce adequate levels of hemoglobin, the protein in red blood cells that carries oxygen throughout the body. This condition can lead to iron deficiency anemia, characterized by fatigue, weakness, and […]
Renal failure, also known as kidney failure, occurs when the kidneys lose their ability to filter waste and excess fluids from the blood. This can lead to the accumulation of harmful substances in the body and disrupt the balance of electrolytes. Renal failure can be classified into two main types: acute renal failure (ARF) and […]
Asthma is a chronic inflammatory disease of the airways characterized by recurrent episodes of wheezing, breathlessness, chest tightness, and coughing, particularly at night or early in the morning. These episodes are associated with widespread but variable airflow obstruction within the lungs that is often reversible either spontaneously or with treatment. Understanding asthma involves exploring its […]
Ischemic heart disease (IHD), also known as coronary artery disease (CAD), is a condition characterized by reduced blood flow to the heart muscle due to the narrowing or blockage of coronary arteries. This reduction in blood flow can lead to symptoms such as angina pectoris and, in severe cases, myocardial infarction (heart attack). The primary […]
