Solubility enhancement techniques for liquid dosage forms are crucial in overcoming the challenges posed by poorly soluble drugs. These techniques aim to improve the solubility, dissolution, and bioavailability of the active pharmaceutical ingredient (API) in liquid formulations. Here’s a detailed note on various solubility enhancement techniques specifically applied to liquid …
DeepakRajput 
Excipients used in the formulation of liquid dosage forms
Excipients are inert substances added to pharmaceutical formulations to improve the stability, bioavailability, palatability, and overall performance of the active pharmaceutical ingredient (API). In the formulation of liquid dosage forms, various excipients play crucial roles in ensuring the medication’s safety, efficacy, and acceptability. Here’s a detailed note on the excipients …
Liquid dosage forms – Advantages, Disadvantages
Liquid dosage forms are pharmaceutical preparations in a liquid state that are administered orally, topically, or by injection. These formulations offer several advantages and disadvantages, and their selection depends on factors such as patient characteristics, the nature of the drug, and the desired therapeutic effect. Here is a detailed note …
Physiological Acid-Base Balance
Physiological acid-base balance refers to the intricate mechanisms within the human body that regulate the pH of bodily fluids, particularly the blood, to maintain a state of homeostasis. This comprehensive overview explores the key components and processes involved in maintaining acid-base balance in the human body. 1. Introduction to Acid-Base …
Geometric Dilutions
Definition Geometric dilution is a technique used in pharmaceutical compounding to ensure the uniform distribution of a potent or concentrated substance throughout a mixture. This method is particularly important when working with small quantities of potent drugs or active ingredients to achieve accurate and consistent dosages in the final product. …
Eutectic Mixtures
Definition A eutectic mixture refers to a specific composition of a mixture of two or more substances that, when melted together, produces a lower melting point than that of any of the individual components. The resulting mixture typically forms a eutectic system with distinct properties. Key Characteristics 1. Lower Melting …
Effervescent Powders
Definition Effervescent powders are a type of pharmaceutical formulation that, upon dissolution in water, produces a fizzing or effervescent reaction, resulting in a carbonated solution. These powders typically contain a combination of an organic acid (such as citric acid) and an alkali metal carbonate (such as sodium bicarbonate), along with …
Dusting Powders – Definition, Composition
Definition Dusting powders are pharmaceutical formulations in powder form that are designed for external application, typically to the skin. These powders serve various purposes, including relieving irritation, absorbing moisture, preventing friction, and treating certain skin conditions. They are finely divided, dry substances intended for topical use. Composition Dusting powders consist …
Official preparations
“Official preparations” typically refer to pharmaceutical formulations that are recognized and listed in official pharmacopeias. Pharmacopeias are authoritative texts that contain information about the properties, standards, and preparations of drugs. These texts are used by healthcare professionals, regulatory authorities, and pharmaceutical manufacturers to ensure the quality, safety, and efficacy of …
Simple and Compound Powders
As pharmaceutical dosage forms, Powders play a crucial role in delivering medications to patients. Their classification into simple and compound powders is based on the complexity of their formulation, considering the number of active and inactive ingredients involved. Simple Powders Definition: Simple powders, known as powder mixtures, consist of one …
