Evaluating semi-solid dosage forms is critical in ensuring their quality, safety, and efficacy. Various tests and assessments are conducted to verify these pharmaceutical formulations’ physical, chemical, and microbiological attributes. Here is an overview of the key aspects considered during the evaluation of semi-solid dosage forms such as ointments, creams, gels, …
DeepakRajput 
Excipients used in semi-solid dosage forms
Excipients are essential components in the formulation of semi-solid dosage forms, contributing to these pharmaceutical preparations’ stability, consistency, and performance. Semi-solid dosage forms, including ointments, creams, gels, and pastes, rely on various excipients to achieve desired physical and chemical properties. Here’s a detailed note on the common excipients used in …
Preparation of Cream and Gels
Crams and gels are prepared by creating semisolid dosage forms for topical application. These formulations are widely used in dermatological and cosmetic applications. Here are general guidelines for preparing creams and gels: Ingredients 1. Base Material: The base combines water and oil, often stabilized by an emulsifier. Common bases include …
Preparation of Ointment and Paste
Preparing ointments and pastes involves creating semisolid dosage forms designed for topical application. These formulations are commonly used in dermatological and topical drug delivery applications. Below are general guidelines for preparing ointments and pastes: Ingredients 1. Base Material: Choose a suitable base, often a combination of oils and fats. Common …
Definitions, classification, mechanisms and factors influencing dermal penetration of drugs
Dermal penetration refers to the process by which drugs or active substances traverse the layers of the skin to reach systemic circulation or exert their therapeutic effects locally. The skin is a barrier that protects the body, and dermal penetration involves overcoming this barrier for effective drug delivery. Classification Dermal …
Semisolid dosage forms- Definition, Types
Pharmaceutical formulations that bridge the consistency between a liquid and a solid are known as semisolid dosage forms. These formulations are designed for topical application to the skin or mucous membranes. They encompass creams, ointments, gels, and pastes, distinguished by their semi-solid nature, enabling easy application, adherence to the skin …
