Diffusion is a fundamental process in biological systems, governing the movement of molecules across cellular and tissue boundaries. Understanding diffusion principles is crucial for comprehending various physiological and cellular processes. Here’s a detailed exploration of diffusion principles in biological systems: Â 1. Definition of Diffusion Diffusion is a fundamental physical process …
DeepakRajput 
Quantitative approach to the factors influencing solubility of drugs
A quantitative approach to understanding the factors influencing the solubility of drugs is essential in the field of pharmaceutical sciences. Solubility, defined as the ability of a substance to dissolve in a solvent, plays a crucial role in drug formulation, delivery, and ultimately, therapeutic efficacy. Several factors impact the solubility …
Solvation and Association
The process of solvation, also known as dissolution, is a kinetic phenomenon that involves the attraction and association of molecules of a solvent with molecules or ions of a solute. This process is quantified by its rate, representing the speed at which it occurs. When a specific solvent dissolves a …
Ideal Solubility Parameters
Ideal solubility parameters are a valuable concept in chemistry and material science that facilitates a comprehensive understanding of how substances interact with solvents. These parameters aid in predicting the solubility behavior of different materials in various solvents, offering insights into their compatibility. The ideal solubility parameters are typically characterized by …
Mechanisms of solute-solvent interactions
A solute dissolves in a solvent through favorable interactions between the two. The free energy changes of both the solute and solvent influence this dissolution. The free energy of solvation encompasses various factors, and the process can be broken down into three stages: (i) A solute (drug) molecule is ‘removed’ …
Solubility and Solubility expression
Solubility, originating from the Latin word ‘solvere,’ meaning to dissolve, refers to the capability of a substance to dissolve in another under specific conditions completely. Typically expressed as the mass of solute per unit volume of solvent, the concentration of a solution is commonly measured in grams per liter. Solubility …
