Ideal solubility parameters are a valuable concept in chemistry and material science that facilitates a comprehensive understanding of how substances interact with solvents. These parameters aid in predicting the solubility behavior of different materials in various solvents, offering insights into their compatibility. The ideal solubility parameters are typically characterized by three key values: dispersion forces … Read more
A solute dissolves in a solvent through favorable interactions between the two. The free energy changes of both the solute and solvent influence this dissolution. The free energy of solvation encompasses various factors, and the process can be broken down into three stages: (i) A solute (drug) molecule is ‘removed’ from its crystal. Segregating the … Read more
Solubility, originating from the Latin word ‘solvere,’ meaning to dissolve, refers to the capability of a substance to dissolve in another under specific conditions completely. Typically expressed as the mass of solute per unit volume of solvent, the concentration of a solution is commonly measured in grams per liter. Solubility indicates the grams of solute … Read more
