5-HT antagonists: Classification, clinical uses, and adverse effects

5-HT antagonists, also known as serotonin receptor antagonists, are a class of drugs that inhibit the action of serotonin, a neurotransmitter that plays a crucial role in various physiological processes. These antagonists block the binding of serotonin to its receptors, thereby modulating its effects. There are different subtypes of serotonin …

Classification of Antihistamines

Antihistamines are a class of drugs designed to counteract the effects of histamine, a natural compound released by the body in response to allergens. Histamine plays a central role in allergic reactions and is responsible for various symptoms such as itching, sneezing, runny nose, and watery eyes. Antihistamines block histamine …

Prostaglandins: Physiological Role, Clinical Implications

Derived from fatty acids, particularly arachidonic acid, which is a component of cell membranes, prostaglandins constitute a group of lipid compounds. These bioactive molecules function as local signaling mediators, exerting a wide range of effects on various physiological processes in the body. By being produced and acting locally at the …

Histamine: Physiological Role, Clinical Applications

Histamine is a biogenic amine, a compound derived from amino acids, that serves as a signaling molecule and neurotransmitter in the body. It is produced and stored in various cells, particularly mast cells and basophils, which are immune system components. When released, histamine plays a key role in several physiological …

Autocoids

Autocoids, short for “autonomous mediators,” refer to a diverse group of naturally occurring substances within the body that act locally to regulate physiological functions. These substances are produced in small quantities and exert their effects near the site of synthesis. Autocoids play essential roles in maintaining homeostasis and mediating various …

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