Aim: Determination of pA₂ Value of Prazosin Using Rat Anococcygeus Muscle (Schild Plot Method) References 1. Arunlakshana, O., & Schild, H.O. (1959). Some quantitative uses of drug antagonists. British Journal of Pharmacology and Chemotherapy, 14(1), 48-58. 2. Ghosh, M.N. (2008). Fundamentals of Experimental Pharmacology (6th ed.). Hilton & Company. 3. Rang, H.P., Dale, M.M., Ritter, … Read more
Aim: Bioassay of Acetylcholine Using Rat Ileum or Colon by Four-Point Bioassay References 1. Ghosh, M.N. (2008). Fundamentals of Experimental Pharmacology (6th ed.). Hilton & Company. 2. Rang, H.P., Dale, M.M., Ritter, J.M., & Flower, R.J. (2015). Rang & Dale’s Pharmacology (8th ed.). Churchill Livingstone. 3. Schild, H.O. (1947). The bioassay of acetylcholine on the … Read more
Aim: Bioassay of Serotonin Using Rat Fundus Strip by Three-Point Bioassay References 1. Ghosh, M.N. (2008). Fundamentals of Experimental Pharmacology (6th ed.). Hilton & Company. 2. Rang, H.P., Dale, M.M., Ritter, J.M., & Flower, R.J. (2015). Rang & Dale’s Pharmacology (8th ed.). Churchill Livingstone. 3. Schild, H.O. (1947). The bioassay of serotonin on the rat … Read more
Aim: Bioassay of Oxytocin Using Rat Uterine Horn by Interpolation Method References 1. Ghosh, M.N. (2008). Fundamentals of Experimental Pharmacology (6th ed.). Hilton & Company. 2. Rang, H.P., Dale, M.M., Ritter, J.M., & Flower, R.J. (2015). Rang & Dale’s Pharmacology (8th ed.). Churchill Livingstone. 3. Schild, H.O. (1947). The bioassay of oxytocin on the rat … Read more
Aim: Bioassay of Histamine Using Guinea Pig Ileum by Matching Method References 1. Ghosh, M.N. (2008). Fundamentals of Experimental Pharmacology (6th ed.). Hilton & Company. 2. Rang, H.P., Dale, M.M., Ritter, J.M., & Flower, R.J. (2015). Rang & Dale’s Pharmacology (8th ed.). Churchill Livingstone. 3. Schild, H.O. (1947). The bioassay of histamine on the guinea … Read more
Aim: Effect of physostigmine and atropine on DRC of acetylcholine using frog rectus abdominis muscle and rat ileum respectively. References: Objective: To study the effect of physostigmine and atropine on the dose-response curve (DRC) of acetylcholine (ACh) using isolated frog rectus abdominis muscle and rat ileum preparations. Principle: Acetylcholine (ACh) is a neurotransmitter that mediates … Read more
Aim: Dose-Response Curve of Acetylcholine Using Frog Rectus Abdominis Muscle References 1. Ghosh, M.N. (2008). Fundamentals of Experimental Pharmacology (6th ed.). Hilton & Company. 2. Rang, H.P., Dale, M.M., Ritter, J.M., & Flower, R.J. (2015). Rang & Dale’s Pharmacology (8th ed.). Churchill Livingstone. 3. Schild, H.O. (1947). The effect of acetylcholine on the frog rectus … Read more
Aim: Study of Diuretic Activity of Drugs Using Rats/Mice References 1. Schmid, B., & Schindler, C. (2003). Diuretic activity of drugs in rodents. Journal of Pharmacological Methods, 50(2), 123-129. 2. Vogel, H.G. (2008). Drug Discovery and Evaluation: Pharmacological Assays (3rd ed.). Springer. 3. Lipschitz, W.L., Haddian, Z., & Kerpcsar, A. (1943). Bioassay of diuretics. Journal … Read more
Aim: Effect of Drugs on Blood Pressure and Heart Rate in Dogs References 1. Hurst, J.W., & Hurst, T.K. (2019). The Heart: A Cardiovascular Physiology and Pharmacology Textbook. Springer. 2. Kwon, J., & Yu, H. (2015). Effects of various drugs on cardiovascular parameters in canine models. Journal of Veterinary Science, 16(4), 345-356. 3. Kearns, G.L., … Read more
Aim: Preparation and Evaluation of Tetracycline Capsules References 1. United States Pharmacopeia (USP 43-NF 38, 2020). 2. Aulton, M.E. (2018). Pharmaceutics: The Science of Dosage Form Design. Churchill Livingstone. 3. Allen, L.V. (2020). Ansel’s Pharmaceutical Dosage Forms and Drug Delivery Systems. Lippincott Williams & Wilkins. Objective To prepare Tetracycline capsules and evaluate their quality in … Read more
