Dopamine is a neurotransmitter, a chemical messenger that transmits signals in the brain and other areas of the nervous system. It plays a crucial role in several physiological functions and is associated with various behavior and mood regulation aspects. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area.
Chemical name: 3,4-dihydroxyphenethylamine
Uses
1. Shock and Hypotension:
Dopamine is used in medical settings to treat shock and hypotension (low blood pressure).
2. Heart Failure:
It may be employed to improve cardiac output in cases of heart failure.
3. Acute Kidney Injury:
Dopamine can be used to increase renal perfusion and urine output in certain cases of acute kidney injury.
Stability and Storage Conditions
Stability: Dopamine solutions are generally stable, but light, temperature, and pH can affect stability.
Storage: It is typically stored in cool, dark conditions. Refrigeration may be required for specific formulations.
Different Types of Formulations
1. Intravenous Infusions:
Dopamine is commonly administered as an intravenous infusion to achieve the desired hemodynamic effects.
Popular Brand Names
Intropin:
Intropin is a well-known brand name for dopamine, and it is widely used in medical settings.