Fluoxetine- Definition, Structure, Uses, Mechanism

Fluoxetine is an antidepressant medication that belongs to the class of drugs known as selective serotonin reuptake inhibitors (SSRIs). It is commonly prescribed to treat various mental health conditions.

Chemical Structure

 Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) with the chemical formula C17H18F3NO.

Uses

1. Major Depressive Disorder (MDD): Doctors commonly prescribe fluoxetine for the treatment of major depressive disorder.

2. Obsessive-compulsive disorder (OCD): It manages obsessive-compulsive disorder.

3. Panic Disorder: Fluoxetine indicates its use for the treatment of panic disorder.

4. Bulimia Nervosa: It is approved for the treatment of bulimia nervosa.

5. Premenstrual Dysphoric Disorder (PMDD): Fluoxetine treats premenstrual dysphoric disorder.

6. Social Anxiety Disorder: In some cases, healthcare providers may prescribe it for social anxiety disorder.

7. Generalized Anxiety Disorder (GAD): It can treat generalized anxiety disorder.

Mechanism of Action

Fluoxetine increases serotonin levels in the brain by inhibiting its reuptake, contributing to its antidepressant and anxiolytic effects.

Dosage Forms

1. Capsules: Fluoxetine is commonly available in capsule form.

2. Tablets: It is also available in tablet form.

3. Oral Solution: Liquid formulations are available for individuals with difficulty swallowing capsules or tablets.

Stability and Storage Conditions

1. Stability: Fluoxetine should be stored in a cool, dry place, protected from light.

2. Temperature: It is generally stable at room temperature.

3. Protection: Protect from extreme temperatures and humidity to prevent degradation.

Common Side Effects

Side effects may include nausea, insomnia, headache, and sexual dysfunction. Side effects should be reported to the healthcare provider if they persist or worsen.

Contraindications

Individuals with a known hypersensitivity to the drug should not take fluoxetine.

Brand Names

1. Prozac: Prozac is a wellknown brand name for fluoxetine.

Individuals must use fluoxetine only under the guidance and prescription of a qualified healthcare professional. Patients should follow the prescribed dosage and report any side effects promptly. Additionally, individuals should inform their healthcare provider of any other medications or supplements they are taking to avoid potential interactions.

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