Suppositories and Pessaries: Definition, Types, Composition, Properties, Advantages, Disadvantages

Screenshot 2024 12 07 185749 Suppositories and Pessaries: Definition, Types, Composition, Properties, Advantages, Disadvantages

Suppositories Suppositories are solid dosage forms designed for insertion into body cavities such as the rectum, vagina, or (occasionally) the urethra, where they melt, dissolve, or soften to release their active ingredients for either local or systemic effects. Characteristics of Suppositories 1. Shape and Size: Rectal suppositories: Torpedo-shaped, approximately 2 cm in length. Vaginal suppositories: … Read more

Preparation of suppositories

Screenshot 2023 11 29 093341 Preparation of suppositories

The preparation of suppositories involves several methods, and the choice of method depends on factors such as the type of base, the active ingredient, and the desired characteristics of the suppository. Here are some common methods of suppository preparation: 1. Fusion or Molding Method Procedure: The base is melted, and the active ingredient is incorporated … Read more

Types of bases for suppositories

Screenshot 2023 11 29 092924 Types of bases for suppositories

Suppositories are formulated with various bases that provide the appropriate consistency, melting or dissolution characteristics, and compatibility with the active ingredients. The choice of base depends on factors such as the suppository’s intended use and the drug’s properties. Common types of bases for suppositories include: 1. Fatty or Oleaginous Bases Examples: Cocoa butter (Theobroma oil), … Read more

Suppositories – Definition, Types, Advantages and Disadvantages

Screenshot 2023 11 29 092451 Suppositories - Definition, Types, Advantages and Disadvantages

Suppositories are solid, medicated dosage forms designed for insertion into body orifices, typically the rectum or vagina, where they gradually melt, dissolve, or disperse. They are formulated to deliver therapeutic substances, such as medications or lubricants, to mucous membranes or for systemic absorption through the rectal or vaginal walls. Suppositories come in various shapes, sizes, … Read more