Effect of physostigmine and atropine on DRC of acetylcholine using frog rectus abdominis muscle and rat ileum respectively

Aim:  Effect of physostigmine and atropine on DRC of acetylcholine using frog rectus abdominis muscle and rat ileum respectively. References: Objective: To study the effect of physostigmine and atropine on the dose-response curve (DRC) of acetylcholine (ACh) using isolated frog rectus abdominis muscle and rat ileum preparations. Principle: Acetylcholine (ACh) is a neurotransmitter that mediates … Read more

Belladonna: General Introduction, Composition, Chemistry, Bio-Sources, Therapeutic Uses, and Commercial Applications

Screenshot 2024 09 17 203446 Belladonna: General Introduction, Composition, Chemistry, Bio-Sources, Therapeutic Uses, and Commercial Applications

General Introduction Belladonna (Atropa belladonna), also known as deadly nightshade, is a perennial herbaceous plant belonging to the Solanaceae family. It is renowned for its toxic properties and medicinal uses due to its content of tropane alkaloids. Historically, belladonna has been used in various cultures for its pharmacological effects, including its ability to dilate the … Read more

Parasympatholytics or anticholinergics or parasympathetic blockers

Screenshot 2024 03 30 135227 Parasympatholytics or anticholinergics or parasympathetic blockers

Parasympatholytics, also known as anticholinergics or parasympathetic blockers, are a class of drugs that antagonize the effects of acetylcholine (ACh) at muscarinic receptors in the parasympathetic nervous system. These drugs inhibit the parasympathetic nervous system’s actions, leading to various physiological effects. Classification of Parasympatholytics Parasympatholytics can be classified based on their chemical structure or their … Read more

Emergency Drugs: Definition, Categories, and Uses

Screenshot 2024 02 15 120057 Emergency Drugs: Definition, Categories, and Uses

Definition Emergency drugs are medications that are administered in critical or life-threatening situations to address immediate medical needs. These drugs are crucial in various healthcare settings, including emergency departments, intensive care units, and pre-hospital care, where rapid intervention is essential to stabilize patients and prevent further harm. Categories of Emergency Drugs 1. Cardiac Arrest and … Read more

Therapeutic activity and pharmaceutical applications of alkaloids

Screenshot 2023 11 16 183705 Therapeutic activity and pharmaceutical applications of alkaloids

Alkaloids, a diverse group of naturally occurring organic compounds, exhibit various therapeutic activities. Many alkaloids have been harnessed for their pharmacological effects and find applications in various pharmaceutical formulations. Here’s a detailed note on the therapeutic activity and pharmaceutical applications of alkaloids: 1. Analgesic and Antinociceptive Activity    – Examples: Morphine, Codeine, Papaverine.    – … Read more

Mydriatics

Screenshot 2023 10 29 210836 Mydriatics

Mydriatics are a class of drugs used in ophthalmology to dilate the pupil. These drugs work by relaxing the iris sphincter muscle, which causes the pupil to enlarge. Mydriatics are primarily used for diagnostic and therapeutic purposes, such as eye examinations and certain eye surgeries. Below is a detailed overview of mydriatics 1. Definition Mydriatics … Read more

Anticholinergic drugs

Screenshot 2023 10 29 121654 Anticholinergic drugs

Anticholinergic drugs, also known as anticholinergic drugs, block the effects of acetylcholine, a neurotransmitter that activates cholinergic receptors in the body. These drugs work by inhibiting the action of acetylcholine at its receptors, leading to a range of physiological effects. Definition Anticholinergic drugs are a class of medications that block the effects of acetylcholine at … Read more