Epilepsy is a chronic neurological disorder characterized by recurrent, unprovoked seizures. These seizures result from abnormal electrical activity in the brain and can vary in type and severity. It is one of the most common neurological conditions, affecting approximately 50 million people worldwide. Pathophysiology of Epilepsy Epilepsy arises from an …
Genetically determined toxicity: Definition, Mechanism, and Management
Genetically Determined Toxicity refers to an individual’s genetic makeup, which can influence their susceptibility to drug-induced toxicity. Genetic variations can affect how a person metabolizes, responds to, and clears drugs, resulting in differences in toxicity levels. Certain individuals may have genetic mutations or polymorphisms in specific genes that make them …
Antimanics: Definition, Classification, Mechanism and Side effects
Definition: Antimanics, also known as mood stabilizers, are a class of medications primarily used to treat bipolar disorder, a mental health condition characterized by episodes of mania or hypomania alternating with episodes of depression. These medications help stabilize mood fluctuations and prevent or reduce the severity of manic or depressive …
Epilepsy: Definition, etiopathogenesis, clinical manifestations, non-pharmacological and pharmacological management
Epilepsy is a neurological disorder characterized by recurrent, unprovoked seizures. Seizures are episodes of abnormal electrical activity in the brain that lead to various symptoms, ranging from brief periods of unconsciousness to unusual movements or sensations. Etiopathogenesis: 1. Idiopathic (Primary) Epilepsy: No identifiable cause; likely genetic factors play a role. …
Anti-convulsant drugs/ anti-epileptic drugs
Anti-convulsant drugs, also known as anti-epileptic drugs (AEDs), are a class of medications designed to prevent or reduce the occurrence of seizures, a hallmark symptom of epilepsy. These drugs act on the central nervous system to stabilise the abnormal electrical activity in the brain that leads to seizures. Anti-convulsant drugs …
Carbamazepine – Structure, Uses, Side effects
Carbamazepine is an anticonvulsant medication and mood stabilizer used in the treatment of various medical conditions, including epilepsy, trigeminal neuralgia, bipolar disorder, and certain neuropathic pain disorders. It belongs to the class of drugs known as antiepileptic or anticonvulsant drugs and works by stabilizing neuronal membranes and reducing abnormal electrical …