Mechanism of Irreversible Cell Injury
Prolonged deprivation of oxygenated blood supply leads to irreversible cellular damage and dysfunction. The process of reversible cell injury can progress to irreversible cell injury, resulting in cell death. This irreversible state is marked by the cell’s inability to reverse mitochondrial and plasma membrane dysfunction even upon reperfusion or reoxygenation. Additional factors contributing to irreversible … Read more
