Macrolides: Classification, Dose, Indications, and Contraindications

Macrolides are a class of antibiotics characterized by a distinctive macrocyclic lactone ring structure. These antibiotics are effective against a wide range of bacteria, particularly Gram-positive bacteria. The mechanism of action of macrolides involves inhibiting bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. This interference disrupts the …

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