The thermodynamic treatment of stability constants involves the use of thermodynamic principles to describe the formation and stability of complexes in solution. Stability constants, also known as formation constants or equilibrium constants, quantify the extent to which a complex is formed from its constituent species. Here’s a detailed note on …
Quantitative approach to the factors influencing solubility of drugs
A quantitative approach to understanding the factors influencing the solubility of drugs is essential in the field of pharmaceutical sciences. Solubility, defined as the ability of a substance to dissolve in a solvent, plays a crucial role in drug formulation, delivery, and ultimately, therapeutic efficacy. Several factors impact the solubility …
Relationship between free energy (G), enthalpy (H), and entropy (S)
The relationship between free energy (G), enthalpy (H), and entropy (S) is described by the Gibbs free energy equation: Δ G = Δ H – T Δ S Let’s break down the relationships between these thermodynamic parameters: 1. Gibbs Free Energy (G): Represents the maximum reversible work that a system …
Bioenergetics – Concept of Free Energy
Bioenergetics is the scientific study of the flow and transformation of energy within living organisms. It explores how cells acquire, convert, store, and utilize energy to sustain life processes. Bioenergetics encompasses the metabolic pathways, reactions, and energy transfers that occur during cellular activities such as growth, reproduction, response to stimuli, …