Approaches to design-controlled release formulations: Based on diffusion, dissolution and ion exchange principles

Controlled release formulations can be designed using various mechanisms that regulate drug release. Three primary principles often employed are diffusion, dissolution, and ion exchange. Each approach involves different methodologies and is tailored to achieve a specific release profile. 1. Diffusion-Based Systems In diffusion-controlled systems, the drug release occurs as the …

Excipients in Pharmaceutical Formulations

 Definition of Excipients Excipients are inactive substances formulated alongside the active pharmaceutical ingredient (API) of a medication. They serve a variety of roles that are critical to the creation, stability, and functionality of the final pharmaceutical product. While excipients do not exert therapeutic effects themselves, they are essential for the …

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