Chemical Properties of Drug Substances

Understanding the chemical properties of drug substances is critical for predicting their stability, compatibility, and overall behavior during formulation, storage, and administration. Here, we detail key chemical processes including hydrolysis, oxidation, reduction, racemization, and polymerization, along with their significance in pharmaceutical development. Hydrolysis – Definition: Hydrolysis is a chemical reaction in which water reacts with […]

Biotransformation

Biotransformation of drugs, also known as drug metabolism, refers to the body’s process of chemically altering a drug to facilitate its elimination from the body. Drug metabolism is a vital pharmacokinetic process that occurs primarily in the liver, although other tissues and organs can also contribute to these reactions. The primary objectives of drug biotransformation […]