Approaches to design-controlled release formulations: Based on diffusion, dissolution and ion exchange principles
Controlled release formulations can be designed using various mechanisms that regulate drug release. Three primary principles often employed are diffusion, dissolution, and ion exchange. Each approach involves different methodologies and is tailored to achieve a specific release profile. 1. Diffusion-Based Systems In diffusion-controlled systems, the drug release occurs as the drug molecules diffuse through a … Read more
