Controlled release formulations can be designed using various mechanisms that regulate drug release. Three primary principles often employed are diffusion, dissolution, and ion exchange. Each approach involves different methodologies and is tailored to achieve a specific release profile. 1. Diffusion-Based Systems In diffusion-controlled systems, the drug release occurs as the …
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Tablet Coating: Types, Materials, Formulation, Methods, Equipment, and Defects
Tablet Coating Tablet coating is a critical process in pharmaceutical manufacturing that involves applying a layer of coating material to the surface of the tablet. This process can serve various purposes, including protecting the drug substance, masking taste, controlling drug release, and improving the tablet’s appearance. Types of Coating 1. …
Excipients in Pharmaceutical Formulations
Definition of Excipients Excipients are inactive substances formulated alongside the active pharmaceutical ingredient (API) of a medication. They serve a variety of roles that are critical to the creation, stability, and functionality of the final pharmaceutical product. While excipients do not exert therapeutic effects themselves, they are essential for the …
