Drug Metabolism: Principles, Phase I, and Phase II Reactions

Introduction: Drug metabolism refers to the enzymatic transformation of drugs and xenobiotics within the body, leading to the formation of metabolites that are often more hydrophilic and easier to excrete. This process plays a crucial role in drug efficacy, bioavailability, and toxicity. Understanding the principles and mechanisms of drug metabolism is essential for optimizing drug … Read more

Biotransformation

Biotransformation of drugs, also known as drug metabolism, refers to the body’s process of chemically altering a drug to facilitate its elimination from the body. Drug metabolism is a vital pharmacokinetic process that occurs primarily in the liver, although other tissues and organs can also contribute to these reactions. The primary objectives of drug biotransformation … Read more

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