Inflammation is regulated by a complex network of chemical mediators that orchestrate the response to injury or infection. These mediators originate from various cells and tissues and include vasoactive amines, lipid mediators, cytokines, chemokines, and other small molecules. They play roles in vasodilation, increased vascular permeability, leukocyte recruitment, and other aspects of the inflammatory response. … Read more
The endocrine system is a complex network of glands that secrete hormones to regulate various bodily functions, including metabolism, growth, reproduction, and homeostasis. Hormones are chemical messengers that travel through the bloodstream to target organs or tissues, where they elicit specific physiological responses. Here is a detailed note on the classification of hormones and their … Read more
Derived from fatty acids, particularly arachidonic acid, which is a component of cell membranes, prostaglandins constitute a group of lipid compounds. These bioactive molecules function as local signaling mediators, exerting a wide range of effects on various physiological processes in the body. By being produced and acting locally at the site of synthesis, prostaglandins influence … Read more
Autocoids, short for “autonomous mediators,” refer to a diverse group of naturally occurring substances within the body that act locally to regulate physiological functions. These substances are produced in small quantities and exert their effects near the site of synthesis. Autocoids play essential roles in maintaining homeostasis and mediating various physiological processes. Examples of autocoids … Read more
