Screenshot 2024 04 20 145930 Physicochemical Properties in Relation to Biological Action

Physicochemical Properties in Relation to Biological Action

Introduction: Physicochemical properties play a crucial role in determining the biological action of drugs. Understanding how these properties influence drug-receptor interactions, pharmacokinetics, and pharmacodynamics is essential for rational drug design and optimization. This note provides a detailed exploration of various physicochemical properties and their significance in biological activity, along with relevant examples. 1. Ionization: Ionization […]

Screenshot 2024 03 02 135055 Methods of analysis: Protein binding, Complexation, and drug action

Methods of analysis: Protein binding, Complexation, and drug action

Analyzing protein binding, complexation, and drug action is crucial to pharmaceutical research and development. Understanding the interactions between drugs and their target proteins provides insights into drug efficacy, safety, and potential side effects. Below is a detailed note on various methods employed to analyze protein binding, complexation, and drug action: Protein Binding Analysis 1. Surface […]