Definition: Parkinson`s disease, or paralysis agitans, is characterized by a resting tremor (involuntary trembling when a limb is in rest), rigidity (inability to initiate movements), and bradykinesia (slowness of movements). The disease results from the degeneration of dopaminergic neurons that arise in the substantial nigra and project to other structures …
Parkinson’s Disease:
Parkinson’s disease (PD) is a progressive neurodegenerative disorder that primarily affects movement. It is characterized by the loss of dopamine-producing neurons in the substantia nigra region of the brain, leading to motor and non-motor symptoms. Etiopathogenesis: 1. Dopamine Depletion: Progressive loss of dopamine-producing neurons in the substantia nigra. 2. Lewy …