Suppositories Suppositories are solid dosage forms designed for insertion into body cavities such as the rectum, vagina, or (occasionally) the urethra, where they melt, dissolve, or soften to release their active ingredients for either local or systemic effects. Characteristics of Suppositories 1. Shape and Size: Rectal suppositories: Torpedo-shaped, approximately 2 …
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Evaluation of suppositories
The evaluation of suppositories involves assessing various physical, chemical, and performance characteristics to ensure their quality, efficacy, and safety. Here are key aspects considered during the evaluation of suppositories: 1. Physical Characteristics Appearance: Check for uniformity in size, shape, and color. Look for any cracks, discoloration, or other visual defects. …
Preparation of suppositories
The preparation of suppositories involves several methods, and the choice of method depends on factors such as the type of base, the active ingredient, and the desired characteristics of the suppository. Here are some common methods of suppository preparation: 1. Fusion or Molding Method Procedure: The base is melted, and …
Types of bases for suppositories
Suppositories are formulated with various bases that provide the appropriate consistency, melting or dissolution characteristics, and compatibility with the active ingredients. The choice of base depends on factors such as the suppository’s intended use and the drug’s properties. Common types of bases for suppositories include: 1. Fatty or Oleaginous Bases …
Suppositories – Definition, Types, Advantages and Disadvantages
Suppositories are solid, medicated dosage forms designed for insertion into body orifices, typically the rectum or vagina, where they gradually melt, dissolve, or disperse. They are formulated to deliver therapeutic substances, such as medications or lubricants, to mucous membranes or for systemic absorption through the rectal or vaginal walls. Suppositories …
Dosage forms – Functions,Classification
The World Health Organization (WHO) defines a dosage form as follows: “A pharmaceutical product, in the form in which it is presented for use, containing one or more active ingredients usually mixed with excipients.” In pharmaceuticals, a unique way to make medicine for patients is a dosage form. It aims …
