Definition: Centrally acting muscle relaxants are a class of medications used to alleviate muscle spasms, stiffness, and pain by acting on the central nervous system (CNS) to reduce skeletal muscle tone and hyperactivity. They are commonly prescribed for musculoskeletal conditions such as back pain, neck pain, spasticity, and fibromyalgia, as well as for certain neurological … Read more
Neuromuscular blocking agents (NMBAs) and skeletal muscle relaxants (peripheral) are classes of drugs used to induce muscle relaxation in surgical and critical care settings. They act at the neuromuscular junction to inhibit or block the transmission of nerve impulses from motor neurons to skeletal muscle fibres, leading to paralysis or relaxation of skeletal muscles. These … Read more
The nervous system (CNS) produces muscle relaxation. These drugs alleviate muscle spasms, stiffness, and associated pain. Unlike peripheral muscle relaxants, which act directly on the muscles, centrally acting muscle relaxants exert their effects by influencing neural pathways in the spinal cord and brain. Classification of Centrally Acting Muscle Relaxants 1. Benzodiazepines: Example: Diazepam. Mechanism: Enhance … Read more
