Neuromuscular blocking agents (NMBAs) and skeletal muscle relaxants (peripheral)

Neuromuscular blocking agents (NMBAs) and skeletal muscle relaxants (peripheral) are classes of drugs used to induce muscle relaxation in surgical and critical care settings. They act at the neuromuscular junction to inhibit or block the transmission of nerve impulses from motor neurons to skeletal muscle fibres, leading to paralysis or relaxation of skeletal muscles. These … Read more

General anaesthetics: Definition, Classification, Pharmacological actions, Dose, Indications and Contraindications

General anaesthetics are a class of drugs that induce a reversible loss of consciousness, sensation, and memory, allowing for the performance of medical procedures or surgery to be pain-free and controlled. These agents act on the central nervous system, producing a state of unconsciousness and muscle relaxation, allowing surgical interventions without causing pain or discomfort … Read more

Cholinergic drugs

Cholinergic drugs are a class of medications that mimic or enhance the effects of acetylcholine. This neurotransmitter plays a vital role in the nervous system and the communication between nerve cells and muscles. Acetylcholine plays a role in various physiological processes, including muscle contraction, regulation of heart rate, gastrointestinal function, and memory. Cholinergic drugs can … Read more

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