Genetically Determined Toxicity refers to an individual’s genetic makeup, which can influence their susceptibility to drug-induced toxicity. Genetic variations can affect how a person metabolizes, responds to, and clears drugs, resulting in differences in toxicity levels. Certain individuals may have genetic mutations or polymorphisms in specific genes that make them more susceptible to adverse drug … Read more
Definition: High-risk drugs are medications that have a higher potential for causing significant harm if used improperly. These drugs often require careful monitoring, specialized administration techniques, and stringent safety protocols due to their inherent risks. Characteristics of High-Risk Drugs 1. Narrow Therapeutic Index (NTI): Drugs with a narrow therapeutic index have a small margin between … Read more
Anti-coagulants are a class of medications that interfere with the body’s natural blood clotting processes. They prevent or treat conditions associated with abnormal blood clot formation, such as deep vein thrombosis (DVT), pulmonary embolism (PE), atrial fibrillation, and certain cardiovascular disorders. By inhibiting clot formation, anti-coagulants reduce the risk of thromboembolic events. Definition Anti-coagulants are … Read more
Atherosclerosis Atherosclerosis is a medical condition characterized by the hardening and narrowing of arteries due to the buildup of plaques consisting of fats, cholesterol, and other substances. Various drugs are used in the management of atherosclerosis. Here’s a brief overview of the key aspects: 1. Definition Atherosclerosis is a chronic vascular disease involving the gradual … Read more
