Venlafaxine – Definition, Uses, Mechanism

Venlafaxine is an antidepressant medication that belongs to the class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs). It treats major depressive disorder, generalized anxiety disorder, social anxiety disorder, and panic disorder.

Uses

1. Major Depressive Disorder (MDD): Doctors commonly prescribe venlafaxine for the treatment of major depressive disorder.

2. Generalized Anxiety Disorder (GAD): It is used to manage generalized anxiety disorder.

3. Social Anxiety Disorder: Venlafaxine indicates its use for the treatment of social anxiety disorder.

4. Panic Disorder: It is used to treat panic disorder.

Mechanism of Action

Venlafaxine works by increasing the levels of serotonin and norepinephrine in the brain, thereby improving mood and alleviating symptoms of depression and anxiety.

Dosage Forms

1. Immediate Release Tablets: Venlafaxine is available in immediate release tablet form.

2. Extended-Release Capsules: Extended-release formulations provide a slower release of the medication, allowing for once-daily dosing.

Common Brand Names

1. Effexor: Effexor is a well-known brand name for venlafaxine.

2. Effexor XR: Effexor XR is the extended-release formulation of venlafaxine.

Dosage and Administration

The venlafaxine dosage varies based on the individual’s condition and response to treatment. It is usually taken orally, with or without food.

Storage Conditions

Store venlafaxine in a cool, dry place, protected from light. Specific storage instructions may vary based on the pharmaceutical formulation.

Stability

Proper storage conditions generally maintain the stability of venlafaxine. It’s important to check the expiration date on the medication packaging and not use expired medication.

Common Side Effects

Side effects may include nausea, dizziness, insomnia, and sexual dysfunction. Report any persistent or severe side effects to the healthcare provider.

Contraindications

Individuals with a known hypersensitivity to the drug and those taking or recently discontinuing monoamine oxidase inhibitors (MAOIs) should avoid venlafaxine.

As with any medication, individuals should use venlafaxine only under the guidance and prescription of a qualified healthcare professional. It’s crucial to follow the prescribed dosage, attend regular followup appointments, and communicate any concerns or side effects to the healthcare provider.

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