Doctors prescribe Vigabatrin as a pharmaceutical medication to treat epilepsy, especially in individuals with complex partial seizures, infantile spasms (West syndrome), and refractory epilepsy. It is also known by its generic name, “Vigabatrin.” Healthcare professionals primarily use Vigabatrin as an anticonvulsant, and it functions by increasing gamma-aminobutyric acid (GABA) levels in the brain. GABA is an inhibitory neurotransmitter that reduces abnormal electrical activity and excitability of neurons, often associated with epileptic seizures. This medication is available in tablet or oral solution powder form and should be taken as prescribed. It is important to follow the prescribed dosage and usage instructions, as well as any specific recommendations provided by your doctor, as Vigabatrin may have potential side effects and interactions with other medications.
Chemical Structure
Vigabatrin has the chemical name (RS)-4-aminohex-5-enoic acid. Its chemical structure consists of a six-carbon aliphatic chain with an amino group at one end and a carbon-carbon double bond at the other end. The molecular formula is C6H11NO2, and it has a molecular weight of approximately 129.16 g/mol. Vigabatrin is available in the form of tablets or powder for oral solution.
Uses
Vigabatrin is a pharmaceutical drug primarily used for the treatment of epilepsy. It has a specific mechanism of action related to the neurotransmitter gamma-aminobutyric acid (GABA). The main uses of Vigabatrin include:
1. Epilepsy: Doctors use Vigabatrin to actively control and prevent epileptic seizures, particularly in individuals with complex partial seizures, infantile spasms (West syndrome), and refractory epilepsy. It functions by increasing GABA levels in the brain, which helps reduce abnormal electrical activity and excitability of neurons, making it effective in controlling seizures.
Stability
Vigabatrin is generally stable when stored correctly, but it can degrade under certain conditions. Factors affecting its stability include:
1. Temperature:Store it at room temperature, typically between 15°C and 30°C (59°F and 86°F).. Avoid exposure to extreme heat or cold.
2. Moisture: Protect Vigabatrin from high humidity and moisture. Store it in a dry environment and ensure the container is tightly closed.
3. Light: Vigabatrin can be sensitive to light. Prolonged exposure to direct sunlight or UV radiation can lead to degradation. It is best to store it in opaque containers or original packaging.
Storage
Proper storage of Vigabatrin is essential to maintain its stability and effectiveness. Here are some guidelines for storing Vigabatrin:
1. Keep in a Cool, Dry Place: Store Vigabatrin in a cool and dry location at room temperature. Avoid storing it in areas with high humidity, such as bathrooms or kitchens.
2. Protect from Sunlight: Shield it from direct sunlight and UV radiation by using opaque containers or keeping it in its original packaging.
3. Secure Container: Make sure to tightly seal the container to prevent moisture from entering.
4. Keep Out of Reach: Store Vigabatrin out of the reach of children and pets.
5. Follow Medical Guidance: Always adhere to the specific storage instructions provided by your healthcare provider or the medication’s manufacturer.
It is important to take Vigabatrin as prescribed by a healthcare professional and not make any changes to the dosage or regimen without consulting your doctor. Use Vigabatrin with caution, as it may have potential side effects and interactions with other medications, and it requires careful monitoring when administered.
